karel roden: 07-08-2020

07-08-2020

7 Авг 2020 в 07:52am

Tetracycline in tablet form is taken orally (inside), washed down with liquid in large quantities. For adults, a single dose is 500 mg 4 times a day, or 500-1000 mg every 12 hours. The maximum daily dose should not exceed 4000 mg.

In the absence of other indications, tablets are used as follows:

  • uncomplicated rectal, endocervical and urethral infections caused by Chlamydiatrachomatis: 500 mg 4 times a day for at least 1 week;
  • acne: 500–2000 mg per day, divided into several doses; with improvement (usually observed after 3 weeks), the daily dose is gradually reduced to a maintenance dose of 500–1000 mg, an adequate remission of the disease should be expected when using the drug every other day or as intermittent therapy;
  • syphilis: 500 mg every 6 hours for 15 days (syphilis at an early stage) or 30 days (syphilis at a late stage);
  • uncomplicated gonorrhea: starting single dose - 1500 mg, then 500 mg every 6 hours for 4 days (total dose of 9000 mg);
  • brucellosis: 500 mg every 6 hours for 3 weeks in combination with intramuscular injection of streptomycin at a dose of 1000 mg every 12 hours for 1 week and 1 time per day for 2 weeks.

For children over 8 years of age, tetracycline is prescribed at a rate of 6.25-12.5 mg / kg every 6 hours or 12.5-25 mg / kg every 12 hours.

Side effects

From the nervous system and sensory organs: increased intracranial pressure, dizziness or instability.

From the cardiovascular system and blood (hematopoiesis, hemostasis): hemolytic anemia, thrombocytopenia, neutropenia.

From the gastrointestinal tract: loss of appetite, nausea, vomiting, diarrhea, glossitis, esophagitis, gastritis, ulceration of the stomach and duodenum, hypertrophy of the papillae of the tongue, dysphagia, hepatotoxic effect, increased activity of hepatic transaminases, hyperbilirubinemia, pancreatic benignitis, anti-tuberculosis, antibiotics.

From the genitourinary system: nephrotoxic effect, azotemia, hypercreatininemia.

Allergic reactions: maculopapular rash, flushing of the skin, angioedema, anaphylactoid reactions, drug systemic lupus erythematosus.

Other: photosensitization, violation of the formation of bone and dental tissue, discoloration of tooth enamel in children, superinfection, candidiasis, hypovitaminosis B.

Features of the reception

Instructions for use of tablets Tetracycline contains recommendations regarding the dose of the drug that should be taken for various diseases.

The average dosage per day for adults is from 0.25 to 0.5 grams 4 times a day. In this case, the maximum dose should not exceed 4 grams of the substance per day.

Children are prescribed medicine in a smaller amount - 6.25-12.5 mg / kg body weight (4 times). Usually, the duration of treatment does not exceed 10 days.

Doses of tetracycline for various diseases:

  • From acne and acne disease. From 500 mg to 2 g several times a day. After three weeks, the dosage is reduced to 0.125-1 grams per day;
  • Brucellosis - every 6 hours should take 0.5 g of the substance for 3 weeks. In this case, treatment is supplemented with intramuscular administration of streptomycin twice a day during the first week;
  • Syphilis - 0.5 g of tetracycline 4 times a day. In the early stages of the disease, an antibiotic is taken for two weeks. With late diagnosis - a month;
  • Gonorrhea - 1.5 g per day, then 0.5 g 4 times a day. The treatment is 4 days.

Effective are tetracycline tablets for diarrhea (250 mg / day.). In this case, the course of admission is up to one week.

The course of therapy depends on the characteristics of the course of the disease. Quite often, doctors prescribe tetracycline (How to Buy Tetracycline Capsules 500 mg with No Prescription) with nystatin. This combination remedy helps fight many bacteria effectively..

Important! Duration of treatment is recommended only by the attending physician. Dosage may be adjusted depending on the condition of the patient and the complexity of the course of the disease..

Side effects

In most cases, the drug is well tolerated by patients. However, sometimes adverse reactions from various systems and organs can be observed. These include:

  1. GIT - intestinal disorders, nausea, anorexia, vomiting, discomfort in the abdomen, heartburn, gastritis, stomatitis, ulcerative lesions of the stomach and duodenum, proctitis, pancreatitis, enterocolitis of staphylococcal etiology, intestinal dysbiosis, pseudomembranous colitis. There is a chance of liver damage, accompanied by pain in the right side, nausea, vomiting, fever.
  2. Genitourinary system - vaginitis, nephritis, acute renal failure, azotemia.
  3. Allergic manifestations - urticaria, anaphylactic shock, skin hyperemia, papular rash, angioedema, exfoliative dermatitis, increased sensitivity of the skin and mucous membranes to UV radiation, Stevens-Johnson syndrome.
  4. Cardiovascular system - inflammation of the serous membrane of the heart (pericarditis).
  5. CNS - headaches, impaired hearing and vision, increased intracranial pressure, photophobia, dizziness, unstable gait.
  6. Hematopoietic organs - anemia, agranulocytosis, thrombocytopenia, eosinophilia, neutropenia, Moshkovich disease.
  7. Respiratory system - bronchospasm.
  8. Laboratory studies - an increase in blood levels of urea, alkaline phosphatase, AcAT, AlAT, nitrogen and bilirubin.
  9. Others - changes in the shade of teeth in children, damage to tooth enamel, pigmentation of the skin, candidiasis, hypersensitivity, itching in the anus and genitals, impaired formation of bone tissue, hypovitaminosis, accelerated proliferation of fungi, slower linear bone growth in patients under 12 years old.

The appearance of any of the above reactions should be the reason for the immediate cessation of medication and contact a doctor. The specialist will study the situation and prescribe antibiotics of another group to continue therapy.



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